High inorganic triphosphatase activities in bacteria and mammalian cells: identification of the enzymes involved.

BACKGROUND: We recently characterized a specific inorganic triphosphatase (PPPase) from Nitrosomonas europaea.This enzyme belongs to the CYTH superfamily of proteins.Many bacterial members of this family are annotated as predicted adenylate cyclases, because one of the founding members is CyaB adenylate cyclase from A.hydrophila.The aim of the pres

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Silver (I) N-Heterocyclic Carbenes Carbosilane Dendritic Systems and Their Imidazolium-Terminated Analogues as Antibacterial Agents: Study of Their Mode of Action

Spherical dendrimers and dendrons containing silver(I) N-heterocyclic carbenes (Ag(I)-NHC) and additionally bow-tie metal-free dendritic systems were synthesized Washcloths in a simple and straightforward synthetic procedure and subsequently characterized.The antibacterial activity was evaluated, and in parallel, a comparative study with the cation

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